FastEval Parkinsonism

Yu-Yuan (Stuart) Yang | Sep 17, 2024 min read

The Motor Disorder Society’s Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) is commonly used to assess bradykinesia, a hallmark symptom of Parkinson’s disease (PD). However, it falls short in capturing the full variability of bradykinesia throughout the day outside of a clinical setting. To address this limitation, we present FastEval Parkinsonism (https://fastevalp.cmdm.tw), a deep learning-based video system that enables users to capture key motion points, estimate severity, and generate summary reports. Using 840 finger-tapping videos from 186 participants (103 with Parkinson’s disease (PD), 24 with atypical parkinsonism (APD), 12 elderly individuals with mild parkinsonism signs (MPS), and 47 healthy controls (HCs)), we apply a dilated convolution neural network combined with two data augmentation techniques. Our model achieves acceptable accuracy (AAC) of 88.0% and 81.5%. The frequency-intensity (FI) measure of thumb-index finger distance emerged as a critical hand parameter for quantifying performance. Additionally, our model demonstrated versatility with multi-angle videos, validated using an external database of over 300 PD patients.

Know more from the reference…

  1. Yang, Y. Y., Ho, M. Y., Tai, C. H., Wu, R. M., Kuo, M. C., and Tseng, Y. J. (Feb. 2024). “FastEval Parkinsonism: an instant deep learning–assisted video-based online system for Parkinsonian motor symptom evaluation.” NPJ Digital Medicine, DOI: 10.1038/s41746-024-01022-x
  2. Yang, Y. Y. (April 2023). “FastEval Parkinsonism: an instant deep learning-based online self-evaluation system for the diagnosis of Parkinson’s symptoms with hand videos using finger tapping.” NTU BEBI (2023 Best Master Thesis Award), DOI:10.6342/NTU202300716